The closures begin at dusk on Saturday, and continue through the end of the race, some time Sunday afternoon.
The area affected by the closure is from Ira Road (about 5 miles south of Peninsula) to just north of the Station Road Bridge near Brecksville (about 7.5 miles north of Peninsula).
Also note that the Lock 29 Trailhead parking lot on Mill Street in Peninsula will be closed during this time. The overflow parking lot just up the street will remain open.
For more information on the Towpath Marathon, visit www.towpathmarathon.net.